May 23, 2025 | By Richard Weisner

Facebook
X
LinkedIn

Quercetin with Bromelain: A Powerful Duo for Immunity, Inflammation, and Allergy Relief

In the world of natural supplements, few combinations offer as broad and impactful a range of benefits as Quercetin with Bromelain. This synergistic duo is gaining popularity for its ability to support the immune system, reduce inflammation, and provide targeted relief for allergies and respiratory conditions — all while being backed by a growing body of clinical research.

Quercetin and Bromelain Capsule Manufacturing

What Is Quercetin?

Quercetin is a natural flavonoid found in many fruits and vegetables, such as apples, onions, berries, and leafy greens. It acts as a potent antioxidant and anti-inflammatory compound, with notable immune-modulating properties.

What Is Bromelain?

Bromelain is a proteolytic enzyme extracted from pineapple stems. It’s widely used for its ability to reduce inflammation, support digestion, and increase the bioavailability of other compounds — most notably, quercetin.

Top 5 Benefits of Quercetin with Bromelain

1. Natural Antihistamine and Allergy Relief

Quercetin stabilizes mast cells, which are responsible for releasing histamine in allergic reactions. This makes it effective for:

  • Seasonal allergies
  • Asthma-related inflammation
  • Sinusitis and nasal congestion

When paired with bromelain, absorption is enhanced, and the anti-inflammatory response is amplified — making it a go-to natural solution for chronic allergy sufferers.

2. Respiratory Health and Asthma Support

Bromelain breaks down mucus and reduces airway inflammation, making breathing easier in conditions like:

  • Asthma
  • Bronchitis
  • Sinusitis

Quercetin complements this by decreasing oxidative stress and improving airway function, making the combo ideal for respiratory resilience.

3. Anti-Inflammatory and Pain Relief

Together, Quercetin and Bromelain modulate the immune response and reduce pro-inflammatory cytokines like TNF-alpha and IL-6. This can help with:

  • Joint pain
  • Muscle soreness
  • Autoimmune flare-ups

4. Immune System Modulation

Unlike synthetic antihistamines that suppress immune reactions entirely, quercetin modulates the immune response. It enhances antiviral defenses while keeping chronic inflammation in check — especially important in today’s immune-conscious environment.

5. Gut and Digestive Health

Bromelain supports digestion by breaking down proteins, while quercetin helps heal gut lining and reduce inflammation associated with food sensitivities — a common concern among those with allergies or autoimmune conditions.

Backed by Research

Numerous clinical studies and meta-analyses support the use of Quercetin and Bromelain in treating upper respiratory tract infections, allergic rhinitis, and inflammation. A 2020 review in Frontiers in Pharmacology confirmed their potential in modulating the immune response without adverse side effects, especially when used in long-term prevention strategies.

Market Insight

With rising interest in natural antihistamines and immune-supporting supplements, the global market for quercetin is projected to grow significantly, particularly in the wake of COVID-era health awareness. Bromelain’s presence in digestive and anti-inflammatory formulations is also seeing robust growth in the U.S. and Europe.

Formulation Tips

The most effective doses in clinical settings typically use:

Quercetin: 250–500 mg per serving

Bromelain: 100–250 mg per serving

Formulated in capsules, chewables, or even functional gummies, this duo is ideal for both adult and pediatric markets.

How Green Star Labs Can Help

Green Star Labs is uniquely positioned to bring your unique magnesium supplement to market:

  • Custom Formulations using clinically-backed ingredients with optimal bioavailability
  • Delivery Formats: capsules, powders, tinctures, gummies, and water-soluble shots
  • Low MOQ options and flexible pricing models
  • In-House R&D and Regulatory Guidance for claims, packaging, and compliance
  • Manufacturing in NSF, cGMP, and FDA-registered facility

Green Star Labs can help you create a standout product backed by science and manufactured to the highest standards.

Let’s Get Started Today!

If an innovative Quercetin and Bromelain formulation  is a good fit for your wellness brand, request a quote now to take the first step to making your vision a reality.

Request A Quote

Request A Quote

Richard Weisner

About Richard Weisner

My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!

Get In Touch  |  Connect on LinkedIn

Recent Posts

FDA Disclaimer: Content published in our Nutraceutical Market Trends blog is for educational purposes and is not intended to represent medical advice. Our audience is B2B brand owners and customers who are interested in developing innovative nutraceutical products. Content that may indicate specific health claims for ingredients or delivery systems has not been evaluated by the FDA. Dietary supplement products manufactured by Green Star Labs, Inc. are not intended to diagnose, treat, cure or prevent any disease.

Green Star Labsoratories, Inc

Green Star Labs Equipment and Capabilites

custom gummies manufacturing

Gummy Full-Scale Starchless Manufacturing

  • Pectin Based – Vegan, Sugar and Sugar-Free custom formulations
  • Standard 4.5g Squares and Custom Molds
  • Multiple production lines – 100,000 to 500,000 Pieces per Shift @ 4.5g
  • Examples: Lion’s Mane/Cordyceps Focus Gummies, Melatonin-less Sleep Gummies, CBD Relax and Revive Gummies, Apple Cider Vinegar Gut Health Gummies, Ashwagandha Adaptogen Gummies, Sugar-Free Creatine Gummy

Small-Scale Gummy R&D

  • Testing the Market, Developing Flavor Profiles, Troubleshooting and problem solving product challenges.
  • Examples: Developing SOP and Formulations for Creatine Gummies, Flavor Masking Caffeine and Cannabinoids

Gummy Co-Packing

  • 5 – 150ct Pouches Packaged in-line – Up to 14,000 pouches per shift @ 5ct .
  • 20 – 90ct Bottles Packaged in-line – Up to 8000 bottles per shift @ 30ct .
  • Examples: 5 and 20ct Snoop Pouches, 30ct Top Fungi Jars, 60ct Fndmntl ACV Jars, 120ct Novos Pouches.

Capsule Full-Scale Starchless Manufacturing

  • Tooling for Size 1, 0, 00 shells (HPMC Standard)
  • Multiple Encapsulators – 60,000 to 1.1M per shift
  • Examples: NAD+ Precursor Supplements, Joint Health, Curcumin and Herbal Blends

Small-Scale Capsule R&D

  • Piloting and Running Trials for efficacy or product performance

Tablet Full-Scale Manufacturing

  •  Tooling for 10mm, 14mm, 16mm, 26mm Diameter Punches
  • 24 Station Press – up to 900,000 per shift
  • Examples: Probiotic Tablets, Chewable herbal remedies, Calcium and mineral blends

Solid Dosage Co-Packing

  • 10ct Blisters formed and sealed – then packaged in-line
  • 15 – 120ct Bottles Packaged in-line – up to 20,000 per shift

Ingestible Liquid Blending

  • Low-Volume Blending through 1800L+ Batches

Bulk Liquid Co-Packing

  • Packed into drums or pails upon request

RTD Shot Bottle Filling

  • 2oz Cosmo Round Bottles @ ~ 10,000 – 15,000 units per shift pending full shrink
  • Manufacturing Lines to Support Flexible Load Balance

RTD Beverage Bottle Filling

  • 8, 12, 16oz and Greater Bottles @ ~ 10,000 units per shift pending full shrink

Topical Cosmetic Blending

  • 50L batch size for High-Viscosity Products: Creams, Gels, Masks
  • 200L batch size for Low-Viscosity Products: Oils, Serums, Treatments

Bulk Cosmetic Co-Packing

  • Packed into drums or pails upon request

Lotion Tube Filling

  • Tooling available for 15ml (0.5oz) – 120ml (4oz) Lotion Tubes
  • Variable Material Specifications
  • Max Through-put 205 tubes/minute

Cosmetic Liquid Sachet Filling

  • Liquid Sachets > 10g minimum sizing
  • Max Through-put 20 sachets/minute

Cosmetic Bottle Co-Packing

  • Variable characteristics and packaging specs acceptable
  • Jars, Bottles, Airless Pumps, Plastic, Glass, Heat Induction Seal

 

 

Free-Flowing Powder Blending

  • Low-Volume Blending through 350kg+ Batches
  • Handles Herbals/Botanicals as well as mixed particle sizes

Large Scale Bulk Powder Co-Packing

  • Packed from 10kg+ bags into boxes

Medium Scale Powder Filling

  • 100g+ – 1kg Pouches and Cannisters

Single-Serving Sachet Filling

  • Single Lane FFS machine auger fed powder blends
  • 10+/minute run speed @ 30g sachets

 

Home  |  About Green Star Labs  |  Our Expertise  |  CertificationsOur Team  |  Contact Us

© Copyright 2025 Green Star Labs, Inc. All rights reserved.

Thank you for your quote request!

Your project specifications have been received and an Account Manager will be in touch with you soon to confirm the details of your project and make recommendations to help you get started with Green Star Labs.