Quercetin is a natural flavonoid found in many fruits and vegetables, such as apples, onions, berries, and leafy greens. It acts as a potent antioxidant and anti-inflammatory compound, with notable immune-modulating properties.
Bromelain is a proteolytic enzyme extracted from pineapple stems. It’s widely used for its ability to reduce inflammation, support digestion, and increase the bioavailability of other compounds — most notably, quercetin.
Quercetin stabilizes mast cells, which are responsible for releasing histamine in allergic reactions. This makes it effective for:
When paired with bromelain, absorption is enhanced, and the anti-inflammatory response is amplified — making it a go-to natural solution for chronic allergy sufferers.
Bromelain breaks down mucus and reduces airway inflammation, making breathing easier in conditions like:
Quercetin complements this by decreasing oxidative stress and improving airway function, making the combo ideal for respiratory resilience.
Together, Quercetin and Bromelain modulate the immune response and reduce pro-inflammatory cytokines like TNF-alpha and IL-6. This can help with:
Unlike synthetic antihistamines that suppress immune reactions entirely, quercetin modulates the immune response. It enhances antiviral defenses while keeping chronic inflammation in check — especially important in today’s immune-conscious environment.
Bromelain supports digestion by breaking down proteins, while quercetin helps heal gut lining and reduce inflammation associated with food sensitivities — a common concern among those with allergies or autoimmune conditions.
Numerous clinical studies and meta-analyses support the use of Quercetin and Bromelain in treating upper respiratory tract infections, allergic rhinitis, and inflammation. A 2020 review in Frontiers in Pharmacology confirmed their potential in modulating the immune response without adverse side effects, especially when used in long-term prevention strategies.
With rising interest in natural antihistamines and immune-supporting supplements, the global market for quercetin is projected to grow significantly, particularly in the wake of COVID-era health awareness. Bromelain’s presence in digestive and anti-inflammatory formulations is also seeing robust growth in the U.S. and Europe.
The most effective doses in clinical settings typically use:
Formulated in capsules, chewables, or even functional gummies, this duo is ideal for both adult and pediatric markets.
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FDA Disclaimer: Content published in our Nutraceutical Market Trends blog is for educational purposes and is not intended to represent medical advice. Our audience is B2B brand owners and customers who are interested in developing innovative nutraceutical products. Content that may indicate specific health claims for ingredients or delivery systems has not been evaluated by the FDA. Dietary supplement products manufactured by Green Star Labs, Inc. are not intended to diagnose, treat, cure or prevent any disease.
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