July 19, 2025 | By GSL Business Development
Why Supplement Brands Must Understand Amazon DSP for Long-Term Sales Success
As competition in the dietary supplement category on Amazon continues to intensify, many brand owners are turning to advanced advertising tools to rise above the noise. One of the most powerful—and often underutilized—tools is Amazon DSP (Demand-Side Platform).
For supplement brands serious about long-term growth, understanding and leveraging Amazon DSP is no longer optional—it’s a strategic necessity.
In this article, we’ll explore what Amazon DSP is, why it matters specifically for supplement brand owners, and how to use it to gain a measurable edge over competitors.
What Is Amazon DSP?
Amazon DSP is a programmatic advertising platform that enables brands to buy display, video, and audio ads both on and off Amazon. Unlike Sponsored Products or Sponsored Brands, which rely on keyword-based campaigns within the Amazon ecosystem, DSP uses shopper behavior and first-party Amazon data to serve highly targeted ads to audiences wherever they are online.
With DSP, supplement brands can:
Retarget shoppers who viewed their product but didn’t purchase
Reach customers who bought similar supplements or searched relevant keywords
Build lookalike audiences based on loyal buyers
Deliver rich media ads on Amazon-owned sites (like IMDb) and external publisher networks
Why Amazon DSP Is Crucial for Supplement Brands
1. Longer Purchase Journeys Require More Touchpoints
Supplements are not always impulse buys. Consumers often research ingredients, read reviews, and compare brands before making a decision. Amazon DSP helps keep your brand visible throughout that decision-making process—even when the shopper has left Amazon.
2. Audience Targeting Goes Beyond Keywords
DSP allows you to target based on real behavioral data, not just search terms. For example, if a customer regularly buys collagen peptides or brain-boosting nootropics, DSP can deliver your similar product right to them—even if they haven’t searched your brand yet.
3. Build Brand Awareness at Scale
With Amazon DSP, you’re not just chasing conversions—you’re building a brand presence across the web. This is especially valuable in the supplement space, where brand trust and perceived expertise are critical for long-term success.
4. Retargeting = Higher ROAS
Retargeting campaigns via DSP often deliver much higher return on ad spend (ROAS) compared to broad targeting. You’re reaching shoppers who’ve already shown interest, nudging them toward conversion with reminders and promotions.
5. Access to Amazon’s Exclusive Audience Insights
DSP gives you insights into shopping behaviors you can’t get elsewhere—such as product views, add-to-cart actions, and competitor interest. These insights can inform not only advertising, but also product development, pricing strategies, and positioning.
Key Use Cases for Supplement Brands Using Amazon DSP
Use Case
Audience Retargeting
Lifestyle & Interest Targeting
Competitor Conquesting
Replenishment Campaigns
Lookalike Audiences
Example
Serve ads to customers who viewed your turmeric supplement but didn’t buy.
Target users interested in fitness, biohacking, or wellness publications.
Show your product to people who bought or viewed a top competitor’s supplement.
Remind customers it’s time to re-order after 30 or 60 days.
Expand reach by targeting users with similar shopping patterns as your best customers.
Getting Started with Amazon DSP
You can access DSP through:
Amazon Managed Services: Amazon runs your campaigns (minimum investment typically required).
Self-Service via Agency Partner: Ideal for brands that want more control and efficiency. Look for agencies with DSP certification and supplement category experience.
Pro Tip: Start with retargeting and competitor conquesting campaigns. These tend to drive the most immediate and measurable results.
Key Takeaway
For supplement brand owners selling on Amazon, DSP is more than just another advertising tool—it’s a strategic weapon in a crowded and commoditized marketplace. Whether you’re looking to scale your customer base, increase brand visibility, or drive repeat purchases, Amazon DSP offers advanced capabilities that go far beyond what Sponsored Ads can achieve alone.
Understanding and mastering Amazon DSP can be the difference between plateaued growth and long-term dominance in the supplement space.
Next Step:
If you haven’t yet explored Amazon DSP, now is the time. Consider working with a specialized Amazon advertising agency or requesting access through Amazon’s managed services team.
The sooner you harness DSP’s power, the sooner you can start turning browsers into buyers—and buyers into loyal customers.
How Green Star Labs Can Help
If you’re in the early stages of building your brand or securing a trademark, consider working with a partner who understands the supplement industry and Amazon compliance. Investing in Brand Registry today can save you thousands in lost revenue and reputation damage tomorrow.
In today’s competitive Amazon marketplace, success hinges on more than just a great idea — it requires expert formulation, trusted certifications, and scalable manufacturing. That’s where Green Star Labs, Inc. stands out as your ideal manufacturing partner.
At Green Star Labs, we specialize in helping supplement brand owners develop and manufacture best-selling products that meet Amazon’s stringent quality standards and consumer expectations. Our certified cGMP, NSF, and Organic manufacturing facilities ensure your products are produced with integrity, safety, and transparency — credentials that matter more than ever to Amazon’s algorithm and your customers.
Whether you’re launching a new product or optimizing an existing formula, our team offers full-service support including:
Custom Formulation & Flavor Development
Capsules, Tablets, Gummies, Powders, and Liquid Formats
Compliance Labeling for Amazon Requirements
Speed-to-Market Manufacturing Turnarounds
Organic, Non-GMO, and Allergen-Free Capabilities
With a proven track record of helping brands scale to 7- and 8-figure sales, we understand the nuances of what sells — and how to make it efficiently and compliantly.
Let Green Star Labs power your next Amazon best-seller.
Contact us today to start building your competitive advantage.
Let’s Get Started Today!
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FDA Disclaimer: Content published in our Nutraceutical Market Trends blog is for educational purposes and is not intended to represent medical advice. Our audience is B2B brand owners and customers who are interested in developing innovative nutraceutical products. Content that may indicate specific health claims for ingredients or delivery systems has not been evaluated by the FDA. Dietary supplement products manufactured by Green Star Labs, Inc. are not intended to diagnose, treat, cure or prevent any disease.
Green Star Labs Equipment and Capabilites
Gummies
Gummy Full-Scale Starchless Manufacturing
- Pectin Based – Vegan, Sugar and Sugar-Free custom formulations
- Standard 4.5g Squares and Custom Molds
- Multiple production lines – 100,000 to 500,000 Pieces per Shift @ 4.5g
- Examples: Lion’s Mane/Cordyceps Focus Gummies, Melatonin-less Sleep Gummies, CBD Relax and Revive Gummies, Apple Cider Vinegar Gut Health Gummies, Ashwagandha Adaptogen Gummies, Sugar-Free Creatine Gummy
Small-Scale Gummy R&D
- Testing the Market, Developing Flavor Profiles, Troubleshooting and problem solving product challenges.
- Examples: Developing SOP and Formulations for Creatine Gummies, Flavor Masking Caffeine and Cannabinoids
Gummy Co-Packing
- 5 – 150ct Pouches Packaged in-line – Up to 14,000 pouches per shift @ 5ct .
- 20 – 90ct Bottles Packaged in-line – Up to 8000 bottles per shift @ 30ct .
- Examples: 5 and 20ct Snoop Pouches, 30ct Top Fungi Jars, 60ct Fndmntl ACV Jars, 120ct Novos Pouches.
Capsules & Tablets
Capsule Full-Scale Starchless Manufacturing
- Tooling for Size 1, 0, 00 shells (HPMC Standard)
- Multiple Encapsulators – 60,000 to 1.1M per shift
- Examples: NAD+ Precursor Supplements, Joint Health, Curcumin and Herbal Blends
Small-Scale Capsule R&D
- Piloting and Running Trials for efficacy or product performance
Tablet Full-Scale Manufacturing
- Tooling for 10mm, 14mm, 16mm, 26mm Diameter Punches
- 24 Station Press – up to 900,000 per shift
- Examples: Probiotic Tablets, Chewable herbal remedies, Calcium and mineral blends
Solid Dosage Co-Packing
- 10ct Blisters formed and sealed – then packaged in-line
- 15 – 120ct Bottles Packaged in-line – up to 20,000 per shift
Beverages
Ingestible Liquid Blending
- Low-Volume Blending through 1800L+ Batches
Bulk Liquid Co-Packing
- Packed into drums or pails upon request
RTD Shot Bottle Filling
- 2oz Cosmo Round Bottles @ ~ 10,000 – 15,000 units per shift pending full shrink
- Manufacturing Lines to Support Flexible Load Balance
RTD Beverage Bottle Filling
- 8, 12, 16oz and Greater Bottles @ ~ 10,000 units per shift pending full shrink
Cosmetics
Topical Cosmetic Blending
- 50L batch size for High-Viscosity Products: Creams, Gels, Masks
- 200L batch size for Low-Viscosity Products: Oils, Serums, Treatments
Bulk Cosmetic Co-Packing
- Packed into drums or pails upon request
Lotion Tube Filling
- Tooling available for 15ml (0.5oz) – 120ml (4oz) Lotion Tubes
- Variable Material Specifications
- Max Through-put 205 tubes/minute
Cosmetic Liquid Sachet Filling
- Liquid Sachets > 10g minimum sizing
- Max Through-put 20 sachets/minute
Cosmetic Bottle Co-Packing
- Variable characteristics and packaging specs acceptable
- Jars, Bottles, Airless Pumps, Plastic, Glass, Heat Induction Seal
Powders
Free-Flowing Powder Blending
- Low-Volume Blending through 350kg+ Batches
- Handles Herbals/Botanicals as well as mixed particle sizes
Large Scale Bulk Powder Co-Packing
- Packed from 10kg+ bags into boxes
Medium Scale Powder Filling
- 100g+ – 1kg Pouches and Cannisters
Single-Serving Sachet Filling
- Single Lane FFS machine auger fed powder blends
- 10+/minute run speed @ 30g sachets
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