July 22, 2025 | By Richard Weisner
Kanna: The Ancient Mood Booster Making a Modern Comeback
Kanna (Sceletium tortuosum) is a succulent plant native to South Africa, used by the indigenous Khoisan people for centuries as a natural mood enhancer, stress reliever, and cognitive stimulant. Traditionally chewed, brewed, or smoked before long journeys or important rituals, Kanna was considered sacred—a plant that gave courage and clarity without sedation.
Today, Kanna is gaining attention in the West as a legal, non-addictive alternative to SSRIs and synthetic nootropics. At its core is mesembrine, a natural serotonin reuptake inhibitor (SRI) that elevates mood, reduces anxiety, and enhances focus—without the crash or dependency.
Potential Benefits of Kanna (Sceletium tortuosum)
Elevates mood by increasing serotonin levels (via SRI activity)*
Reduces anxiety without sedation*
Enhances focus and cognitive clarity*
May support social interaction and reduce stress responses*
Works synergistically with adaptogens and nootropics*
Clinical studies have shown that Kanna extracts like Zembrin® can reduce amygdala reactivity (the brain’s fear center) while improving executive function and working memory.
Market Outlook
The global nootropics market is expected to reach $29.2 billion by 2028, growing at a CAGR of 13.2%.
Mood support supplements are one of the fastest-growing categories post-pandemic, with consumers seeking alternatives to pharmaceuticals.
Kanna’s benefits align with top search terms like anxiety relief, natural antidepressant, focus without caffeine, and plant-based calm.
With legal status in most countries and a rapidly growing wellness market, Kanna is poised for explosive growth—especially in stacks.
The Ultimate Kanna Stack for Gummies or Capsules
Green Star Labs specializes in developing cutting-edge stacks using rare actives like Kanna alongside top-tier nutraceuticals. From gummies to capsules to functional beverages, we ensure your formulation hits both efficacy and compliance standards.
Ingredient
Kanna Extract
L-Theanine
Rhodiola Rosea
Lion’s Mane Extract
Magnesium Glycinate
Vitamin B6
Piperine (Black Pepper Extract)
5-HTP
GABA
Dose
25 mg
200 mg
150 mg
500 mg
100 mg
25 mg
10 mg
25 mg
50 mg
Function
Natural SRI, mood upliftment, calm focus
Synergizes with Kanna for relaxed clarity
Adaptogen for stress resilience
Neurogenesis, long-term cognitive support
Nervous system relaxation
Neurotransmitter synthesis (serotonin, dopamine)
Boosts absorption and bioavailability
Boosts serotonin precursor levels
Additional calming support
Why This Stack Works
Fast-acting calm from Kanna + L-Theanine
Stress resilience from adaptogens like Rhodiola
Mood & mental clarity from Lion’s Mane + B6
Smooth delivery enhanced by Piperine
Legal, non-drowsy, and non-habit forming
Perfect for those who want Zen-like calm without sedation, motivation without stimulants, and mood support without pharmaceuticals.
Product Opportunities
Focus & Calm Gummies
Mood Capsules
Social Support Chews
Anxiety Relief Shots
Cognitive Clarity + Stress Blend
How Green Star Labs Can Help
Green Star Labs specializes in custom gummy formulation with bioavailability-enhancing strategies like emulsification, micronization, and dual-layer gummies. Whether you’re targeting men’s health, sexual wellness, or vitality stacks—we can help you craft a standout Kanna stack gummy tailored to your brand identity.
- Custom Formulations using clinically-backed ingredients with optimal bioavailability
- Delivery Formats: capsules, powders, tinctures, gummies, and water-soluble shots
- Low MOQ options and flexible pricing models
- In-House R&D and Regulatory Guidance for claims, packaging, and compliance
- Manufacturing in NSF, cGMP, and FDA-registered facility
Green Star Labs can help you create a standout product backed by science and manufactured to the highest standards.
Let’s Get Started Today!
If an innovative Kanna Gummy Supplement formulation is a good fit for your wellness brand, request a quote now to take the first step to making your vision a reality.
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About Richard Weisner
My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!
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FDA Disclaimer: Content published in our Nutraceutical Market Trends blog is for educational purposes and is not intended to represent medical advice. Our audience is B2B brand owners and customers who are interested in developing innovative nutraceutical products. Content that may indicate specific health claims for ingredients or delivery systems has not been evaluated by the FDA. Dietary supplement products manufactured by Green Star Labs, Inc. are not intended to diagnose, treat, cure or prevent any disease.
Green Star Labs Equipment and Capabilites
Gummies
Gummy Full-Scale Starchless Manufacturing
- Pectin Based – Vegan, Sugar and Sugar-Free custom formulations
- Standard 4.5g Squares and Custom Molds
- Multiple production lines – 100,000 to 500,000 Pieces per Shift @ 4.5g
- Examples: Lion’s Mane/Cordyceps Focus Gummies, Melatonin-less Sleep Gummies, CBD Relax and Revive Gummies, Apple Cider Vinegar Gut Health Gummies, Ashwagandha Adaptogen Gummies, Sugar-Free Creatine Gummy
Small-Scale Gummy R&D
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- Examples: Developing SOP and Formulations for Creatine Gummies, Flavor Masking Caffeine and Cannabinoids
Gummy Co-Packing
- 5 – 150ct Pouches Packaged in-line – Up to 14,000 pouches per shift @ 5ct .
- 20 – 90ct Bottles Packaged in-line – Up to 8000 bottles per shift @ 30ct .
- Examples: 5 and 20ct Snoop Pouches, 30ct Top Fungi Jars, 60ct Fndmntl ACV Jars, 120ct Novos Pouches.
Capsules & Tablets
Capsule Full-Scale Starchless Manufacturing
- Tooling for Size 1, 0, 00 shells (HPMC Standard)
- Multiple Encapsulators – 60,000 to 1.1M per shift
- Examples: NAD+ Precursor Supplements, Joint Health, Curcumin and Herbal Blends
Small-Scale Capsule R&D
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Tablet Full-Scale Manufacturing
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Solid Dosage Co-Packing
- 10ct Blisters formed and sealed – then packaged in-line
- 15 – 120ct Bottles Packaged in-line – up to 20,000 per shift
Beverages
Ingestible Liquid Blending
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Bulk Liquid Co-Packing
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RTD Shot Bottle Filling
- 2oz Cosmo Round Bottles @ ~ 10,000 – 15,000 units per shift pending full shrink
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RTD Beverage Bottle Filling
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Cosmetics
Topical Cosmetic Blending
- 50L batch size for High-Viscosity Products: Creams, Gels, Masks
- 200L batch size for Low-Viscosity Products: Oils, Serums, Treatments
Bulk Cosmetic Co-Packing
- Packed into drums or pails upon request
Lotion Tube Filling
- Tooling available for 15ml (0.5oz) – 120ml (4oz) Lotion Tubes
- Variable Material Specifications
- Max Through-put 205 tubes/minute
Cosmetic Liquid Sachet Filling
- Liquid Sachets > 10g minimum sizing
- Max Through-put 20 sachets/minute
Cosmetic Bottle Co-Packing
- Variable characteristics and packaging specs acceptable
- Jars, Bottles, Airless Pumps, Plastic, Glass, Heat Induction Seal
Powders
Free-Flowing Powder Blending
- Low-Volume Blending through 350kg+ Batches
- Handles Herbals/Botanicals as well as mixed particle sizes
Large Scale Bulk Powder Co-Packing
- Packed from 10kg+ bags into boxes
Medium Scale Powder Filling
- 100g+ – 1kg Pouches and Cannisters
Single-Serving Sachet Filling
- Single Lane FFS machine auger fed powder blends
- 10+/minute run speed @ 30g sachets
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